To resolve "Publish" and "Save Draft" button and similar issues, disable your plugins one at a time until you find the source of the issue. Generally, this will be due to two or more plugins trying to use the same resources (for example, JQuery or other Java-based tools).
In addition, it could be that there is a problem with your browser. A common resolution is to empty the browser's cache. Please consult the documentation for your preferred browser to learn how to do this.
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